Built around 1855, the Meeme House Inn was located along the Green Bay Road. It was built by farmer and new immigrant, Michael Herr. The typical rate was around $1 a day, which included supper, lodging, breakfast and feed and stabling for a team of horses. The building had several small overnight rooms, a tavern on the first floor and a large beautiful ballroom on the second. Voting also took place inside until a new poll house was built in 1900.
It has been said that during the Civil War a rally took place in the ballroom and the next day the Civil War volunteers walked to Manitowoc to join the unit. The Meeme House Inn was owned by the Herr family until 1906 when it was purchased by Peter DeGrott. DeGrott operated the Inn until 1909 when it was sold to Joe Schwartz. After Joe's death in 1947, his wife Minnie ran the tavern until 1955. The Meeme House Tavern was then passed on to their daughter Valeria and become well known as Sessler's Meeme House.
The Meeme House is similar to other stagecoach inns across Wisconsin including the Dousman Inn (Brookfield, 1843); the Hawks Inn (Delafield, 1846); the Wade House (Greenbush, 1850); and the Okauchee House (Okauchee, 1850-1851). The Meeme House Inn is the only site to have its original livery stable.